i have an accord, turbo, on auto was putting 200whp. It can be done but i hated the way car was. So i swapped out the auto for a manual, drove it with the auto ecu in and loved every second of it though the whole fun experience lasted only 15minutes cuz i am having troubles with a manual ecu. But yeah, if you want to spend 5G+ to rebuild your tranny by Level10, go for it.
ps: Some guy did the whole level10 rebuild and swore that every time the gear shifted, it felt like the tranny jumped out. So, i recommend you do some research on level10 before you actually go for it