My dad owns a 98 V6. The transmission has been replaced, but it happened in the mid to high 200's. Also, if he had taken the car in when the transmission first started to slip, then he may have been able to get away with just a torque converter. I was actually driving the car when it really hit the fan. It wouldn't go into 3rd or 4th gear, just 1 and 2.
Overall, though, it's a great car. I think it's up to 320-340K, and the last non-scheduled maintenance was, well, I can't think of the actual name, but it's basically a screen and o-ring gasket on the vtec solenoid. Oil started leaking there lightly a long time ago, and then it got pretty steady several months ago, and my brother actually replaced it for him.