is it a jdm or usdm. if its a usdm you might have problems, the usdm has a immobilizer in the unit and is actuated by the ignition in typr r vehicles only. the jdm should be fine. Running the itr ecu ? depending on your compression is how it will function. I tried to run one of these in my wifes ls/vtec with 9.4 compression. The fuel mapping was too rich so it ran like crap. You also have the alternative to add a vafc controller too just in case. p73-ao2 etc = usdm, p73-oo2or 003 = jdm.
good luck.