10.8:1 is okay specially if its forged. just TUNE on a dyno and buy the right injector size, and use good/high octane gas. i would buy a wideband and i would keep it in the car all the time, not just for tuning
however the best area to be in if you are going FI is 8.8:1-9.8:1 depending on size and type of engine. on hondas the 9range does good like tloc said. call cometic and get a thicker HG and ARP head studs