OBD0 or Non-OBD: Pre-92. Sucks for tuning, but you can buy Ebay chips for it. Has 2 1-wire O2 sensors that are essential for VTEC.
OBD1: 92-95. Best for tuning, compatible with Hondata, Uberdata, etc...has one 4-wire o2 sensor and is DEFINITELY the best for tuning.
OBD2A: 96-98. You can't chip it or anything, but I think you can have it reprogrammed. Has 2 4-wire o2 sensors.
OBD2B: 99-01. Worst of all. Same O2 sensor setup as OBD2A.